FROM BIOINFORMATICS TO CLINICAL APPLICATIONS: A NOVEL PROGNOSTIC MODEL OF CUPROPTOSIS-RELATED GENES BASED ON SINGLE-CELL RNA SEQUENCING DATA IN HEPATOCELLULAR CARCINOMA

Abstract Objective and methods To ascertain the connection between cuproptosis-related genes (CRGs) and the prognosis of hepatocellular carcinoma (HCC) via single-cell RNA sequencing (scRNA-seq) and RNA sequencing (RNA-seq) data, relevant data were downloaded from the GEO and TCGA databases.The differentially expressed CRGs (DE-CRGs) were filtered

Increasing pressures on land resources requires increased land use efficiency.Over 900 million ha of sandy soils throughout the world are extensively used for agricultural crop production, most requiring nutrient inputs.Although use of humic substances together with inorganic fertilizer as soil amendments Waist Bag has been introduced, their synerg

Abstract Background The use of newer azoles as prophylaxis in hematological patients undergoing stem cell transplantation or immunosuppressive chemotherapy has been shown to decrease the risk of developing invasive fungal disease (IFD).However, the cost-effectiveness of such a strategy is dependent on the local epidemiology of Scarves IFD.We conduc

Changes in the mobility patterns have evoked concerns about the future availability of certain raw materials necessary to produce alternative drivetrains and related batteries.The goal of this article is to determine if resource use aspects are adequately reflected within life cycle assessment (LCA) case studies of electric vehicles (EV).Overall, 1